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Literature summary for 2.7.8.13 extracted from

  • Azzolina, B.A.; Yuan, X.; Anderson, M.S.; El-Sherbeini, M.
    The cell wall and cell division gene cluster in the Mra operon of Pseudomonas aeruginosa: Cloning, production, and purification of active enzymes (2001), Protein Expr. Purif., 21, 393-400.
    View publication on PubMed

Application

Application Comment Organism
medicine opportunistic pathogen causing infections in patients with burns or neutropenia and involved in respiratory tract infections of cystic fibrosis patients, pathway of peptidoglycan biosynthesis is both essential and unique to bacteria, making it an attractive target for antibiotic research Pseudomonas aeruginosa

Cloned(Commentary)

Cloned (Comment) Organism
cloning of the murE-dd1B region, the cell wall biosynthesis and cell division gene cluster, expressed in Escherichia coli BL21(DE3) Pseudomonas aeruginosa

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Pseudomonas aeruginosa 5737
-
membrane
-
Pseudomonas aeruginosa 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-NAc-muramoyl-pentapeptide + acceptor Pseudomonas aeruginosa
-
UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
r

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-NAc-muramoyl-pentapeptide + acceptor
-
Pseudomonas aeruginosa UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
r