Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Streptomyces chattanoogensis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces chattanoogensis | H9N836 | - |
- |
Streptomyces chattanoogensis | H9N839 | - |
- |
Streptomyces chattanoogensis L10 | H9N836 | - |
- |
Streptomyces chattanoogensis L10 | H9N839 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA agarose column chromatography | Streptomyces chattanoogensis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CoA-[4'-phosphopantetheine] + apo-[acyl-carrier protein] | - |
Streptomyces chattanoogensis | adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein] | - |
? | |
CoA-[4'-phosphopantetheine] + apo-[acyl-carrier protein] | - |
Streptomyces chattanoogensis L10 | adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein] | - |
? | |
additional information | the enzyme catalyzes the phosphopantetheinylation of acyl carrier proteins in both type I polyketide synthases and type II polyketide synthases | Streptomyces chattanoogensis | ? | - |
? | |
additional information | the enzyme catalyzes the phosphopantetheinylation of acyl carrier proteins in type II polyketide synthases and fatty acid synthases | Streptomyces chattanoogensis | ? | - |
? | |
additional information | the enzyme catalyzes the phosphopantetheinylation of acyl carrier proteins in both type I polyketide synthases and type II polyketide synthases | Streptomyces chattanoogensis L10 | ? | - |
? | |
additional information | the enzyme catalyzes the phosphopantetheinylation of acyl carrier proteins in type II polyketide synthases and fatty acid synthases | Streptomyces chattanoogensis L10 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AcpS | - |
Streptomyces chattanoogensis |
phosphopantetheinyl transferase | - |
Streptomyces chattanoogensis |
PPT | - |
Streptomyces chattanoogensis |
PPTase | - |
Streptomyces chattanoogensis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
4'-phosphopantetheine | - |
Streptomyces chattanoogensis |
General Information | Comment | Organism |
---|---|---|
malfunction | inactivation of the enzyme abolishes production of natamycin but not the spore pigment | Streptomyces chattanoogensis |
physiological function | overexpression of the enzyme not only increases the natamycin production by about 40% but also accelerates productions of both natamycin and the spore pigment | Streptomyces chattanoogensis |