Literature summary for 2.7.9.1 extracted from

Haines, D.S.; Burnell, J.N.; Doyle, J.R.; Llewellyn, L.E.; Motti, C.A.; Tapiolas, D.M.
Translation of in vitro inhibition by marine natural products of the C4 acid cycle enzyme pyruvate Pi dikinase to in vivo C4 plant tissue death (2005), J. Agric. Food Chem., 53, 3856-3862.

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Inhibitors

Inhibitors	Comment	Organism	Structure
ilimaquinone	uncompetitive/mixed type versus pyruvate and versus ATP, 48% inhibition of C4 acid cycle evolution. IC50: 0.292 mM	Zea mays

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + pyruvate + phosphate	Zea mays	C4 acid cycle enzyme	AMP + phosphoenolpyruvate + diphosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Zea mays	P11155	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + pyruvate + phosphate	C4 acid cycle enzyme	Zea mays	AMP + phosphoenolpyruvate + diphosphate	-	?

Synonyms

Synonyms	Comment	Organism
PPDK	-	Zea mays
pyruvate P1 dikinase	-	Zea mays

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.292	-	uncompetitive/mixed type versus pyruvate and versus ATP, 48% inhibition of C4 acid cycle evolution. IC50: 0.292 mM	Zea mays	ilimaquinone

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Release 2023.1 (January 2023)