Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
glycosome | - |
Trypanosoma evansi | 20015 | - |
additional information | the enzyme is released from whole trypomastigotes upon addition of digitonin at increasing concentrations | Trypanosoma evansi | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Trypanosoma evansi |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + pyruvate + phosphate | Trypanosoma evansi | - |
AMP + phosphoenolpyruvate + diphosphate | - |
r | |
ATP + pyruvate + phosphate | Trypanosoma evansi TEVA 1 | - |
AMP + phosphoenolpyruvate + diphosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma evansi | - |
isolated from a horse | - |
Trypanosoma evansi TEVA 1 | - |
isolated from a horse | - |
Purification (Comment) | Organism |
---|---|
purification of glycosomes, the enzyme is released from whole trypomastigotes upon addition of digitonin at increasing concentrations | Trypanosoma evansi |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
trypomastigote | Trypanosoma evansi does not undergo stage-dependent differentiations, it occurs only as bloodstream form | Trypanosoma evansi | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.016 | - |
purified glycosomes, pH 7.2, 28°C | Trypanosoma evansi |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + pyruvate + phosphate | - |
Trypanosoma evansi | AMP + phosphoenolpyruvate + diphosphate | - |
r | |
ATP + pyruvate + phosphate | - |
Trypanosoma evansi TEVA 1 | AMP + phosphoenolpyruvate + diphosphate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
PPDK | - |
Trypanosoma evansi |
pyruvate phosphate dikinase | - |
Trypanosoma evansi |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
28 | - |
assay at | Trypanosoma evansi |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Trypanosoma evansi |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
AMP | - |
Trypanosoma evansi | |
ATP | - |
Trypanosoma evansi |
General Information | Comment | Organism |
---|---|---|
evolution | Trypanosoma evansi does not undergo stage-dependent differentiations, it occurs only as bloodstream forms, the metabolic pattern of this parasite is not identical to that of the bloodstream form of Trypanosoma brucei, modelling, overview | Trypanosoma evansi |
metabolism | the enzyme PPDK is an auxiliary enzyme of glycolytic metabolism present in glycosomes, modelling, overview | Trypanosoma evansi |
physiological function | the enzyme plays an important role in the maintenance of the ATP/ADP balance in glycosomes in this life-cycle stage of the parasite, as well as contributes in part to its glycolytic flux | Trypanosoma evansi |