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Literature summary for 2.8.1.3 extracted from

  • Libiad, M.; Motl, N.; Akey, D.L.; Sakamoto, N.; Fearon, E.R.; Smith, J.L.; Banerjee, R.
    Thiosulfate sulfurtransferase-like domain-containing 1 protein interacts with thioredoxin (2018), J. Biol. Chem., 293, 2675-2686 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
1.04 A resolution crystal structure displays an exposed active site that is distinct from that of rhodanese and mercaptopyruvate sulfurtransferase Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
11
-
glutathione 37°C, pH 7.4 Homo sapiens
17
-
thiosulfate cosubstrate glutathione, 37°C, pH 7.4 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8NFU3 cf. EC 2.8.1.1
-

Source Tissue

Source Tissue Comment Organism Textmining
colon apical localization in colonic crypts Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
thiosulfate + cyanide
-
Homo sapiens sulfite + thiocyanate
-
?
thiosulfate + glutathione
-
Homo sapiens ? + glutathione disulfide
-
?
thiosulfate + thioredoxin
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
TSTD1
-
Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.43
-
thiosulfate 37°C, pH 7.4 Homo sapiens

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.025
-
thiosulfate 37°C, pH 7.4 Homo sapiens
0.039
-
glutathione 37°C, pH 7.4 Homo sapiens