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Literature summary for 2.8.1.7 extracted from

  • Kurihara, T.; Mihara, H.; Kato, S.; Yoshimura, T.; Esaki, N.
    Assembly of iron-sulfur clusters mediated by cysteine desulfurases, IscS, CsdB and CSD, from Escherichia coli (2003), Biochim. Biophys. Acta, 1647, 303-309.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
IcsU forms disulfide bonds with IcsS and stimulates its activity 6fold Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-cysteine + [enzyme]-cysteine Escherichia coli
-
L-alanine + [enzyme]-S-sulfanylcysteine
-
?
additional information Escherichia coli facilitates the formation of the iron-sulfur cluster of ferredoxin in vitro ?
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
3 cysteine desulfurases: IscS, CsdB and CSD
-

Purification (Commentary)

Purification (Comment) Organism
copurified with IscU Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-cysteine + [enzyme]-cysteine
-
Escherichia coli L-alanine + [enzyme]-S-sulfanylcysteine
-
?
additional information facilitates the formation of the iron-sulfur cluster of ferredoxin in vitro Escherichia coli ?
-
?