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Literature summary for 2.8.1.7 extracted from
- Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly (2006), J. Biol. Chem., 281, 12344-12351.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
cytosolic isoform, overexpression in Pichia pastoris | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-cysteine + c-ISCS | - |
Homo sapiens | L-alanine + c-ISCS-SSH | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | enzyme forms a complex in vitro with overexpressed cytosolic scaffold protein ISCU | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| c-ISCS | - |
Homo sapiens |
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