KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.028 | - |
derapril | enzyme from jejunum microsomes | Rattus norvegicus | |
0.033 | - |
derapril | enzyme from liver microsomes | Rattus norvegicus | |
0.041 | - |
derapril | enzyme from jejunum cytosol | Rattus norvegicus | |
0.094 | - |
oxybutynin | enzyme from liver cytosol | Homo sapiens | |
0.101 | - |
derapril | enzyme from liver cytosol | Rattus norvegicus | |
0.123 | - |
oxybutynin | enzyme from liver cytosol | Homo sapiens | |
0.245 | - |
imidapril | enzyme from liver microsomes | Homo sapiens | |
0.346 | - |
imidapril | enzyme from jejunum microsomes | Rattus norvegicus | |
0.382 | - |
imidapril | enzyme from jejunum cytosol | Rattus norvegicus | |
0.397 | - |
imidapril | enzyme from liver cytosol | Homo sapiens | |
0.46 | - |
derapril | enzyme from liver microsomes | Homo sapiens | |
1.118 | - |
derapril | enzyme from liver cytosol | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
cytosol | - |
Homo sapiens | 5829 | - |
microsome | - |
Rattus norvegicus | - |
- |
microsome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P23141 | - |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
jejunum | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl acetate + H2O | - |
Rattus norvegicus | 4-nitrophenol + acetate | - |
? | |
4-nitrophenyl acetate + H2O | - |
Homo sapiens | 4-nitrophenol + acetate | - |
? | |
derapril + H2O | - |
Rattus norvegicus | N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)glycine + ethanol | - |
? | |
derapril + H2O | - |
Homo sapiens | N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)glycine + ethanol | - |
? | |
imidapril + H2O | - |
Rattus norvegicus | imidaprilat + ? | - |
? | |
imidapril + H2O | - |
Homo sapiens | imidaprilat + ? | - |
? | |
additional information | does not utilize oxybutynin | Rattus norvegicus | ? | - |
? | |
oxybutynin + H2O | - |
Homo sapiens | 2-cyclohexyl-2-phenylglycolic acid + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
carboxylesterase 1 | - |
Rattus norvegicus |
carboxylesterase 1 | - |
Homo sapiens |
CES1 | - |
Rattus norvegicus |
CES1 | - |
Homo sapiens |