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Literature summary for 3.1.1.1 extracted from

  • Chen, C.; Liu, Y.; Shi, X.; Desneux, N.; Han, P.; Gao, X.
    Elevated carboxylesterase activity contributes to the lambda-cyhalothrin insensitivity in quercetin fed Helicoverpa armigera (Huebner) (2017), PLoS ONE, 12, e0183111 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.1

Inhibitors

Inhibitors Comment Organism Structure
S,S,S-tributyl phosphorotrithioate DEF, dynergist DEF can inhibit the activity of carboxylesterase in insect Helicoverpa armigera

Organism

Organism UniProt Comment Textmining
Helicoverpa armigera
-
 adults collected from Handan, Hebei Province, China
-

Source Tissue

Source Tissue Comment Organism Textmining
larva third-instar larvae Helicoverpa armigera
-
midgut
-
 Helicoverpa armigera
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-nitrophenyl acetate + H2O crude enzyme extract Helicoverpa armigera 2-nitrophenol + acetate
-
 ?
lambda-cyhalothrin + H2O
-
 Helicoverpa armigera 3-phenoxybenzyl alcohol + lambda-cyhalothric acid
-
 ?

Synonyms

Synonyms Comment Organism
CarE
-
 Helicoverpa armigera

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Helicoverpa armigera

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Helicoverpa armigera

Expression

Organism Comment Expression
Helicoverpa armigera carboxylesterase is significantly induced and activity increased by quercitin within 120 h in Helicoverpa armigera larvae after feeding on quercetin for 48 h up

General Information

General Information Comment Organism
metabolism metabolic pathways of lambda±cyhalothrin, overview Helicoverpa armigera
physiological function elevated carboxylesterase activity and increased hydrolytic metabolic capacity towards lambda-cyhalothrin contributes to the lambda-cyhalothrin insensitivity in quercetin fed Helicoverpa armigera. S,S,S-Tributyl phosphorotrithioate (DEF) treatment shows a synergistic effect on lambda-cyhalothrin toxicity to quercetin-fed Helicoverpa armigera Helicoverpa armigera