Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.103 extracted from

  • Komatsuzawa, H.; Sugai, M.; Ohta, K.; Fujiwara, T.; Nakashima, S.; Suzuki, J.; Lee, C.; Suginaka, H.
    Cloning and characterization of the fmt gene which affects the methicillin resistance level and autolysis in the presence of triton X-100 in methicillin-resistant Staphylococcus aureus (1997), Antimicrob. Agents Chemother., 41, 2355-2361 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.103

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + H2O Staphylococcus aureus
-
 [(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + D-alanine
-
 ?
[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + H2O Staphylococcus aureus KSA8
-
 [(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + D-alanine
-
 ?

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus O50608
-
-
Staphylococcus aureus KSA8 O50608
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + H2O
-
 Staphylococcus aureus [(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + D-alanine
-
 ?
[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + H2O
-
 Staphylococcus aureus KSA8 [(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + D-alanine
-
 ?

Synonyms

Synonyms Comment Organism
FMT
-
 Staphylococcus aureus

General Information

General Information Comment Organism
malfunction enzyme mutants have increased susceptibilities to beta-lactams in the presence or absence of 0.02% Triton X-100 compared with the susceptibilities of the parent strains, while the susceptibilities of the mutants to other antibiotics are not altered Staphylococcus aureus
physiological function the enzyme is involved in cell wall synthesis Staphylococcus aureus