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Literature summary for 3.1.1.3 extracted from
- Rapid exchange of pancreatic lipase between triacylglycerol droplets (2004), Biochim. Biophys. Acta, 1682, 72-79.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| S152G | inactive mutant, the inactive enzyme mutant S152G binds to tricaprylin in a water emulsion interface competiting with the active enzyme hydrolyzing the substrate, overview | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| orlistat | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Homo sapiens | - |
| pancreas | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the inactive enzyme mutant S152G binds to tricaprylin in a water emulsion interface competiting with the active enzyme hydrolyzing the substrate, overview | Homo sapiens | ? | - |
? | |
| tricaprylin + H2O | - |
Homo sapiens | dicaprylin + caprylate | - |
? | |
| tricaprylin + H2O | - |
Sus scrofa | dicaprylin + caprylate | - |
? | |
| triolein + H2O | substrate is an olive oil/gum arabic emulsion containing radiolabeled triolein in presence of bile acids and lecithin at rate-limiting concentrations, rapid exchange of the enzyme between two different triacylglycerol droplets measured by a non-exchanging enzyme inhibitor in one of the droplets | Sus scrofa | diolein + oleate | - |
? | |
| triolein + H2O | substrate is an olive oil/gum arabic emulsion containing radiolabeled triolein in presence of bile acids and lecithin at rate-limiting concentrations, rapid exchange of the enzyme between two different triacylglycerol droplets measured by a non-exchanging enzyme inhibitor orlistat in one of the droplets | Homo sapiens | diolein + oleate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Pancreatic lipase | - |
Homo sapiens |
| Pancreatic lipase | - |
Sus scrofa |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
| 37 | - |
assay at | Sus scrofa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Homo sapiens |
| 7.5 | - |
assay at | Sus scrofa |
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Release 2023.1 (January 2023)
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