Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | hepatic lipase activity increases with increased visceral fat | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | hepatic lipase deficiency reduces body fate stores and reduces adipose tissue macrophage content, fully prevents development of hepatic steatosis, and is consistent with reduced inflammation and a lean phenotype, overview | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipocyte | - |
Mus musculus | - |
adipose tissue | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
hepatic lipase | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | hepatic lipase deficiency reduces body fate stores and protects against diet-induced obesity | Mus musculus |
physiological function | hepatic lipase-mediated lipoprotein hydrolysis provides free fatty acids for energy, storage, and nutrient signaling and may play a role in energy homeostasis. The enzyme activity favors weight gain and obesity | Mus musculus |