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Literature summary for 3.1.1.32 extracted from

  • Belaunzaran, M.L.; Wainszelbaum, M.J.; Lammel, E.M.; Gimenez, G.; Aloise, M.M.; Florin-Christensen, J.; Isola, E.L.
    Phospholipase A1 from Trypanosoma cruzi infective stages generates lipid messengers that activate host cell protein kinase C (2007), Parasitology, 134, 491-502.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular secretion by the infective stages, secretion in enhanced by formation of metacyclic forms Trypanosoma cruzi
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membrane bound, mainly Trypanosoma cruzi 16020
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Trypanosoma cruzi the parasite enzyme of the infective stages generates lipid messengers that activate host cell protein kinase C, infection of Vero cells with the pathogen leads to an altered lipid composition with the appearance of free fatty acids, diacylglycerol, and lysophosphatidylcholine, overview, the enzyme might play an important role in host cell-parasite interaction preceding invasion ?
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?

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
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-
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Source Tissue

Source Tissue Comment Organism Textmining
amastigote infective stage, high enzyme activity Trypanosoma cruzi
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epimastigote non-infective stage, low enzyme activity Trypanosoma cruzi
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trypomastigote infective stage, high enzyme activity Trypanosoma cruzi
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the parasite enzyme of the infective stages generates lipid messengers that activate host cell protein kinase C, infection of Vero cells with the pathogen leads to an altered lipid composition with the appearance of free fatty acids, diacylglycerol, and lysophosphatidylcholine, overview, the enzyme might play an important role in host cell-parasite interaction preceding invasion Trypanosoma cruzi ?
-
?

Synonyms

Synonyms Comment Organism
Plase A1
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Trypanosoma cruzi