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Literature summary for 3.1.1.32 extracted from

  • Keller, P.M.; Rust, T.; Murphy, D.J.; Matico, R.; Trill, J.J.; Krawiec, J.A.; Jurewicz, A.; Jaye, M.; Harpel, M.; Thrall, S.; Schwartz, B.
    A high-throughput screen for endothelial lipase using HDL as substrate (2008), J. Biomol. Screen., 13, 468-475.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in CHO cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
GSK264220A
-
Homo sapiens
tetrahydrolipstatin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
heparin-Sepharose column chromatography and Superdex 200 gel filtration Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
high-density lipoprotein + H2O
-
Homo sapiens fatty acid + ?
-
?

Synonyms

Synonyms Comment Organism
endothelial lipase
-
Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1
-
high-density lipoprotein
-
Homo sapiens