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Literature summary for 3.1.1.4 extracted from

  • Ghomashchi, F.; Yu, B.Z.; Mihelich, E.D.; Jain, M.K.; Gelb, M.H.
    Kinetic characterization of phospholipase A2 modified by manoalogue (1991), Biochemistry, 30, 9559-9569.
    View publication on PubMed
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
1-hexadecyl-3-trifluoroethylglycero-sn-2-phosphomethanol MJ33, competitive inhibitor Apis mellifera
1-hexadecyl-3-trifluoroethylglycero-sn-2-phosphomethanol MJ33, competitive inhibitor Naja naja
1-hexadecyl-3-trifluoroethylglycero-sn-2-phosphomethanol MJ33, competitive inhibitor Sus scrofa
manoalogue synthetic analogue of the sea sponge-derived manoalide, time dependent irreversible loss of activity: modification of lysine residues Apis mellifera
manoalogue synthetic analogue of the sea sponge-derived manoalide, time dependent irreversible loss of activity: modification of lysine residues Naja naja
manoalogue synthetic analogue of the sea sponge-derived manoalide, time dependent irreversible loss of activity: modification of lysine residues Sus scrofa
omega-bromo-4-nitroacetophenone
-
 Apis mellifera
omega-bromo-4-nitroacetophenone
-
 Naja naja
omega-bromo-4-nitroacetophenone
-
 Sus scrofa

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
 Sus scrofa
Ca2+
-
 Apis mellifera
Ca2+
-
 Naja naja

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phospholipids + H2O Sus scrofa
-
 ?
-
 ?
phospholipids + H2O Naja naja
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Apis mellifera
-
-
-
Naja naja
-
 cobra
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Sus scrofa
-
venom
-
 Apis mellifera
-
venom
-
 Naja naja
-

Storage Stability

Storage Stability Organism
-20°C Sus scrofa
-20°C Apis mellifera
-20°C Naja naja

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-dimyristol-sn-glycero-phosphomethanol lithium salt + H2O
-
 Sus scrofa myristic acid + 1-myristoyl-sn-glycerophosphomethanol
-
 ?
1,2-dimyristol-sn-glycero-phosphomethanol lithium salt + H2O
-
 Apis mellifera myristic acid + 1-myristoyl-sn-glycerophosphomethanol
-
 ?
1,2-dimyristol-sn-glycero-phosphomethanol lithium salt + H2O
-
 Naja naja myristic acid + 1-myristoyl-sn-glycerophosphomethanol
-
 ?
phospholipids + H2O
-
 Sus scrofa ?
-
 ?
phospholipids + H2O
-
 Naja naja ?
-
 ?

Subunits

Subunits Comment Organism
monomer
-
 Sus scrofa
monomer
-
 Apis mellifera
monomer
-
 Naja naja