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Literature summary for 3.1.1.4 extracted from

  • Wickramaratna, J.C.; Fry, B.G.; Aguilar, M.I.; Kini, R.M.; Hodgson, W.C.
    Isolation and pharmacological characterization of a phospholipase A2 myotoxin from the venom of the Irian Jayan death adder (Acanthophis rugosus) (2003), Br. J. Pharmacol., 138, 333-342.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
4-bromophenacyl bromide 1.8 mM, prevents myotoxicity caused by the enzyme Acanthophis rugosus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
13810
-
mass spectrometry Acanthophis rugosus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Acanthophis rugosus enzyme causes myotoxicity but no significant neurotoxicity ?
-
?

Organism

Organism UniProt Comment Textmining
Acanthophis rugosus
-
death adder
-

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Acanthophis rugosus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-dithio-deheptanoyl phosphatidylcholine + H2O
-
Acanthophis rugosus ?
-
?
additional information enzyme causes myotoxicity but no significant neurotoxicity Acanthophis rugosus ?
-
?

Synonyms

Synonyms Comment Organism
Acanmyotoxin-1
-
Acanthophis rugosus