Crystallization (Comment) | Organism |
---|---|
wild-type and mutant A12T/H15D/M20L/E71N, in ligand-free form and in complex with inhibitor MJ33 | Sus scrofa |
Protein Variants | Comment | Organism |
---|---|---|
A12T/H15D/M20L/E71N | catalytic activity similar to wild-type | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol | i.e. MJ33 | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.2 | - |
phosphatidylcholine | mutant A12T/H15D/M20L/E71N, pH 8.0, 24°C | Sus scrofa | |
0.2 | - |
phosphatidylcholine | wild-type, pH 8.0, 24°C | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | P00592 | isoform IB PLA | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pancreas | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphatidylcholine + H2O | - |
Sus scrofa | 1-acylglycerophosphocholine + fatty acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IB PLA2 | - |
Sus scrofa |