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Literature summary for 3.1.1.4 extracted from

  • Shimada, A.; Ohkura, N.; Hayashi, K.; Samejima, Y.; Omori-Satoh, T.; Inoue, S.; Ikeda, K.
    Subunit structure and inhibition specificity of alpha-type phospholipase A2 inhibitor from Protobothrops flavoviridis (2008), Toxicon, 51, 787-796.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
alpha-type phospholipase A2 inhibitor i.e. PLIalpha, an about 75 kDa protein purified from the plasma of the Habu snake Protobothrop flavoviridis, a trimer of two homologous subunits, PLIalpha-A and PLIalpha-B, each of which contains one C-type lectin-like domain, subunit structure and inhibiton specificity, overview. The protein recovers from 6 M guanidine HCl treatment to about 33% inhibition of enzyme activity at 25°C Protobothrops flavoviridis

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Protobothrops flavoviridis
-
-

Organism

Organism UniProt Comment Textmining
Protobothrops flavoviridis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Protobothrops flavoviridis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphocholine + H2O fluorometric determination Protobothrops flavoviridis ?
-
?

Synonyms

Synonyms Comment Organism
alpha-type phospholipase A2
-
Protobothrops flavoviridis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Protobothrops flavoviridis