Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.5 extracted from

  • Flieger, A.; Neumeister, B.; Cianciotto, N.P.
    Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine (2002), Infect. Immun., 70, 6094-6106.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.5

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli, overexpression in Legionella pneumophila completely protects from the toxic effects of lysophosphatidylcholine Legionella pneumophila

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular major secreted lysophospholipase A Legionella pneumophila
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-monopalmitoyllysophosphatidylglycerol + H2O Legionella pneumophila
-
 glycerophosphoglycerol + palmitic acid
-
 ?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O Legionella pneumophila
-
 glycerophosphocholine + palmitate
-
 ?
2-lysophosphatidylcholine + H2O Legionella pneumophila
-
 glycerophosphocholine + a carboxylate
-
 ?

Organism

Organism UniProt Comment Textmining
Legionella pneumophila Q8GNM7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-monopalmitoyllysophosphatidylglycerol + H2O
-
 Legionella pneumophila glycerophosphoglycerol + palmitic acid
-
 ?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
-
 Legionella pneumophila glycerophosphocholine + palmitate
-
 ?
2-lysophosphatidylcholine + H2O
-
 Legionella pneumophila glycerophosphocholine + a carboxylate
-
 ?

Synonyms

Synonyms Comment Organism
lysophospholipase A
-
 Legionella pneumophila
plaA
-
 Legionella pneumophila