Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Triton X-100 | stimulates membrane-bound enzyme | Acanthamoeba castellanii |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
deoxycholate | soluble enzyme | Acanthamoeba castellanii | |
glutathione | membrane-bound enzyme, no inhibition of the soluble enzyme | Acanthamoeba castellanii | |
Hg2+ | - |
Acanthamoeba castellanii | |
NEM | soluble enzyme, no inhibition of the membrane-bound enzyme | Acanthamoeba castellanii | |
SDS | soluble and membrane-bound enzyme | Acanthamoeba castellanii | |
Triton X-100 | soluble enzyme | Acanthamoeba castellanii | |
Zn2+ | - |
Acanthamoeba castellanii |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.083 | - |
lysophosphatidylcholine | at low substrate concentrations | Acanthamoeba castellanii | |
0.26 | - |
lysophosphatidylcholine | at high substrate concentrations | Acanthamoeba castellanii |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Acanthamoeba castellanii | 16020 | - |
plasma membrane | - |
Acanthamoeba castellanii | 5886 | - |
soluble | - |
Acanthamoeba castellanii | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acanthamoeba castellanii | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
lysophosphatidylcholine + H2O | - |
Acanthamoeba castellanii | glycerophosphorylcholine + unesterified fatty acid | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
and a second optimum at pH 8.0, membrane-bound enzyme | Acanthamoeba castellanii |
7 | - |
and a second optimum at pH 9.5, soluble enzyme | Acanthamoeba castellanii |
8 | - |
and a second optimum at pH 6.5, membrane-bound enzyme | Acanthamoeba castellanii |
9.5 | - |
and a second optimum at pH 7.0, soluble enzyme | Acanthamoeba castellanii |