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Literature summary for 3.1.1.53 extracted from

  • Takematsu, H.; Diaz, S.; Stoddart, A.; Zhang, Y.; Varki, A.
    Lysosomal and cytosolic sialic acid 9-O-acetylesterase activities can be encoded by one gene via differential usage of a signal peptide-encoding exon at the N terminus (1999), J. Biol. Chem., 274, 25623-25631.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
endosome
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Mus musculus 5768
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lysosome
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Mus musculus 5764
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additional information the cytosolic and lysomomal form of the enzyme are found in very different subcellular compartments, but they are encoded by a single gene by different usage of a signal peptide-encoding exon at the N terminus Mus musculus
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-

Organism

Organism UniProt Comment Textmining
Mus musculus P70665
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-

Source Tissue

Source Tissue Comment Organism Textmining
brain restricted distribution, strongest expression of the lysosomal enzyme Mus musculus
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liver restricted distribution, strongest expression of the lysosomal enzyme Mus musculus
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ovary restricted distribution, strongest expression of the lysosomal enzyme Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-9-O-acetylneuraminate + H2O
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Mus musculus N-acetylneuraminate + acetate
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?

Synonyms

Synonyms Comment Organism
cytosolic sialic acid 9-O-acetylesterase
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Mus musculus
lysosomal sialic acid 9-O-acetylesterase
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Mus musculus