Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the distinctive apparent inhibition constants for NEM-induced inhibition of 11-cis retinyl-palmitate hydrolase and the all-trans-retinyl-palmitate hydrolase activity suggest a fundamental difference in the amino acid composition at the active site of the enzyme(s) | Bos taurus | |
NEM | inhibits all-trans retinyl-palmitate hydrolase and 11-cis-retinyl-palmitate hydrolase activity of the liver enzyme, inhibits all-trans-retinyl-palmitate hydrolase activity of the pigment epithelium, 11-cis-retinyl-palmitate hydrolase activity of the pigment epithelium is unaffected | Bos taurus | |
triolein | inhibits all-trans retinyl-palmitate hydrolase and 11-cis-retinyl-palmitate hydrolase activity of the liver enzyme, inhibits all-trans-retinyl-palmitate hydrolase activity of the pigment epithelium, 11-cis-retinyl-palmitate hydrolase activity of the pigment epithelium is unaffected | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Bos taurus | - |
retinal pigment epithelium | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
all-trans-retinyl palmitate + H2O | - |
Bos taurus | all-trans-retinol + palmitate | - |
? |