Application | Comment | Organism |
---|---|---|
synthesis | engineering of Rhodospirillum rubrum to synthesize a heteropolymer of mainly 3-hydroxydecanoic acid and 3-hydroxyoctanoic acid from CO- and CO2-containing artificial synthesis gas (syngas) using Pseudomonas putida 3-hydroxyacyl acyl carrier protein thioesterase, a medium-chain-length fatty acid coenzyme A ligase, and an medium-chain-length polyhydroxyalkanoate synthase. A heteropolymer of 3-hydroxydecanoic acid and 3-hydroxyoctanoic acid accumulates to up to 7.1% (wt/wt) of the cell dry weight. The recombinant strains are able to partially degrade the polymer, and the deletion of isoform PhaZ2 does not reduce mobilization of the accumulated polymer significantly. Mutation C176A in the active site of PhaZ2 leads to a slight increase in poly-3-hydroxyalkanoate accumulation | Rhodospirillum rubrum |
Protein Variants | Comment | Organism |
---|---|---|
C176A | mutation C176A in the active site leads to a slight increase in poly-3-hydroxyalkanoate accumulation in a recombinant strain | Rhodospirillum rubrum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rhodospirillum rubrum | Q2RNZ5 | - |
- |
Rhodospirillum rubrum DSM 467 | Q2RNZ5 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
Rru_A3356 | - |
Rhodospirillum rubrum |