Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | Q9GJT2 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
ESD | - |
Sus scrofa |
Organism | Comment | Expression |
---|---|---|
Sus scrofa | foot-and-mouth disease virus infection triggers ESD expression | up |
General Information | Comment | Organism |
---|---|---|
physiological function | overexpression of ESD significantly suppresses foot-and-mouth disease virus FMDV replication. Knockdown of ESD expression enhances virus replication. Sendai-virus-induced interferon signaling is enhanced by upregulation of ESD. ESD protein enhances IRF3 phosphorylation during FMDV infection. Overexpression of ESD also promotes the expression of various antiviral interferon-stimulated genes, and knockdown of ESD impairs the expression of these antiviral genes during FMDV infection | Sus scrofa |