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Literature summary for 3.1.2.12 extracted from

  • Uotila, L.; Koivusalo, M.
    S-Formylglutathione hydrolase (1981), Methods Enzymol., 77, 320-325.
    View publication on PubMed
Search for more literature for 3.1.2.12

General Stability

General Stability Organism
stabilization by 2-mercaptoethanol or dithiothreitol Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
5,5'-dithiobis(2-nitrobenzoate)
-
 Homo sapiens
arsenite
-
 Homo sapiens
HgCl2
-
 Homo sapiens
iodoacetate
-
 Homo sapiens
N-ethylmaleimide
-
 Homo sapiens
p-hydroxymercuribenzoate
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.12
-
 S-acetylglutathione
-
 Homo sapiens
0.29
-
 S-formylglutathione
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 2 * 30000, SDS-PAGE Homo sapiens
52000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4050
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-acetylglutathione + H2O
-
 Homo sapiens glutathione + acetate
-
 ?
S-formylglutathione + H2O
-
 Escherichia coli glutathione + formate
-
 ?
S-formylglutathione + H2O
-
 Homo sapiens glutathione + formate
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 30000, SDS-PAGE Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.9 7.1
-
 Homo sapiens

pH Stability

pH Stability pH Stability Maximum Comment Organism
5 8
-
 Homo sapiens