Literature summary for 3.1.21.3 extracted from

Gubler, M.; Braguglia, D.; Meyer, J.; Piekarowicz, A.; Bickle, T.A.
Recombination of constant and variable modules alters DNA sequence recognition by type IC restriction-modification enzymes (1992), EMBO J., 11, 233-240.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Escherichia coli	a bacterial population may switch the recognition sequence of its type I restriction-modification system by single recombination events and thus is able to maintain a prokaryotic analogue of the immune system of variable specificity	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	enzyme EcoR124 and EcoDXXI	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
duplex DNA + ATP	-	Escherichia coli	double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate	-	?
additional information	a bacterial population may switch the recognition sequence of its type I restriction-modification system by single recombination events and thus is able to maintain a prokaryotic analogue of the immune system of variable specificity	Escherichia coli	?	-	?

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Release 2023.1 (January 2023)