Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
EcoR124I | - |
Purification (Comment) | Organism |
---|---|
mixture of two enzyme species, the larger species has the stoichiometry R2M2S1, the smaller species has the stoichiometry of R1M2S1.only the R2M2S1 complex is capable of DNA cleavage, the R1M2S1 complex retains ATPase activity | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
duplex DNA + ATP | - |
Escherichia coli | double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | two enzyme species, the larger species has the stoichiometry R2M2S1, the smaller species has the stoichiometry of R1M2S1. Only the R2M2S1 complex is capable of DNA cleavage, the R1M2S1 complex retains ATPase activity. The HsdS subunit determines specificity, the HsdM subunit is responsible for DNA methylation, the HsdR subunit is required for restriction. The HsdM subunit and the HsdS subunit can also form an independent DNA methyltransferase with a subunit stoichiometry of M2S1 | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
EcoR124I | - |
Escherichia coli |