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Literature summary for 3.1.21.3 extracted from
- Type I restriction enzymes and their relatives (2014), Nucleic Acids Res., 42, 20-44.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ArdA protein | - |
Escherichia coli | |
| ArdB protein | - |
Escherichia coli | |
| Ocr protein | - |
Escherichia coli |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Escherichia coli |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| duplex DNA + ATP | Escherichia coli | type I enzymes recognize bipartite DNA sequences comprising two half-sequences separated by a gap, for example, AACNNNNNNGTGC (AAC N6 GTGC) where N=any base | double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| duplex DNA + ATP | type I enzymes recognize bipartite DNA sequences comprising two half-sequences separated by a gap, for example, AACNNNNNNGTGC (AAC N6 GTGC) where N=any base | Escherichia coli | double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| pentamer | - |
Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Eco377I | - |
Escherichia coli |
| Eco394I | - |
Escherichia coli |
| Eco585I | - |
Escherichia coli |
| Eco646I | - |
Escherichia coli |
| Eco826I | - |
Escherichia coli |
| Eco851I | - |
Escherichia coli |
| Eco912I | - |
Escherichia coli |
| EcoAI | - |
Escherichia coli |
| EcoBI | - |
Escherichia coli |
| EcoDI | - |
Escherichia coli |
| EcoDXXI | - |
Escherichia coli |
| EcoEI | - |
Escherichia coli |
| EcoGIV | - |
Escherichia coli |
| EcoKI | - |
Escherichia coli |
| EcoprrI | - |
Escherichia coli |
| EcoR124 | - |
Escherichia coli |
| HsdR | restriction subunit | Escherichia coli |
| REase | - |
Escherichia coli |
| type I R-M enzyme | - |
Escherichia coli |
| type I restriction enzyme | - |
Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Escherichia coli | |
| S-adenosyl-L-methionine | - |
Escherichia coli | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | EcoprrI is an apoptosis enzyme | Escherichia coli |
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Release 2023.1 (January 2023)
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