Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of mutant strain MG1655rnc-14::DELTATn10 | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Escherichia coli MG1655 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
RNase III | - |
Escherichia coli |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.9 | - |
assay at | Escherichia coli |
General Information | Comment | Organism |
---|---|---|
metabolism | the RNase III-mediated regulatory pathway functions to modulate corA expression and, in turn, the influx of metal ions transported by CorA in Escherichia coli | Escherichia coli |
physiological function | the steady-state levels of metal transporter corA mRNA as well as the degree of cobalt influx into the cell are dependent on cellular concentrations of the enzyme RNase III. Enzyme RNase III cleavage constitutes a rate-determining step for corA mRNA degradation, downregulation of corA expression by the enzyme, overview. Introduction of point mutations in RNase III cleavage sites C-122G, U-153A, and A-152G of corA mRNA abolishes the enzyme cleavage activity on corA mRNA and results in prolonged half-lives of the mRNA | Escherichia coli |