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BRENDA support

Literature summary for 3.1.26.5 extracted from

  • Doersen, C.J.; Guerrier-Takada, C.; Altman, S.; Attardi, G.
    Characterization of an RNase P activity from HeLa cell mitochondria. Comparison with the cytosol RNase P activity (1985), J. Biol. Chem., 260, 5942-5949.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
ATP above 2 mM, progressively inhibitory Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Cs+ less effective in activation than K+ Homo sapiens
K+
-
Homo sapiens
Li+ less effective in activation than K+ Homo sapiens
Mg2+ required Homo sapiens
Na+ less effective in activation than K+ Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
ribonucleoprotein requires a RNA component Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pre-tRNA precursor + H2O cleaves the precursor to E. coli suppressor tRNATyr at the same site as E. coli RNase P Homo sapiens tRNA + 5'-oligoribonucleotide
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.7 8.7
-
Homo sapiens