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Literature summary for 3.1.26.5 extracted from

  • Gobert, A.; Gutmann, B.; Taschner, A.; Goessringer, M.; Holzmann, J.; Hartmann, R.K.; Rossmanith, W.; Giege, P.
    A single Arabidopsis organellar protein has RNase P activity (2010), Nat. Struct. Mol. Biol., 17, 740-744.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
PRORP1-PRORP3, phylogenetic analysis, overview Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast PRORP1 Arabidopsis thaliana 9507
-
mitochondrion PRORP1 Arabidopsis thaliana 5739
-
nucleus PRORP2 and PRORP3 are two paralogues of PRORP1 Arabidopsis thaliana 5634
-

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chloroplastic pre-tRNAPhe + H2O
-
Arabidopsis thaliana chloroplastic tRNAPhe + 5' leader of tRNA
-
?
mitochondrial pre-tRNACys + H2O
-
Arabidopsis thaliana mitochondrial tRNACys + 5' leader of tRNA
-
?

Subunits

Subunits Comment Organism
More two aspartates are essential for the activity of PRORP1 Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
PRORP1
-
Arabidopsis thaliana
proteinaceous RNase P
-
Arabidopsis thaliana
RNase P
-
Arabidopsis thaliana

General Information

General Information Comment Organism
evolution evolutionary history of PRORP, overview Arabidopsis thaliana
additional information Arabidopsis thaliana PRORP1 can replace the bacterial ribonucleoprotein RNase P in Escherichia coli cells Arabidopsis thaliana
physiological function the ubiquitous endonuclease RNase P is responsible for the 5' maturation of tRNA precursors. In Arabidopsis thaliana mitochondria and plastids, a single protein called proteinaceous RNase P, PRORP1, can perform the endonucleolytic maturation of tRNA precursors that defines RNase P activity. In addition, PRORP1 is able to cleave tRNA-like structures involved in the maturation of plant mitochondrial mRNAs Arabidopsis thaliana