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Literature summary for 3.1.3.16 extracted from

  • Martin, M.; Potente, M.; Janssens, V.; Vertommen, D.; Twizere, J.C.; Rider, M.H.; Goris, J.; Dimmeler, S.; Kettmann, R.; Dequiedt, F.
    Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis (2008), Proc. Natl. Acad. Sci. USA, 105, 4727-4732.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.16

Inhibitors

Inhibitors Comment Organism Structure
okadaic acid
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Do11.10 cell
-
 Homo sapiens
-
HEK-293T cell
-
 Homo sapiens
-
HUVEC cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PP2A dephosphorylates all four 14-3-3 binding sites in the class IIa histone deacetylase 7, PP2A constitutively dephosphorylates histone deacetylase 7 to control its biological functions as a regulator of T cell apoptosis and endothelial cell functions Homo sapiens ?
-
 ?
phosphorylated histone deacetylase 7 + H2O
-
 Homo sapiens histone deacetylase 7 + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
PP2A
-
 Homo sapiens
protein phosphatase 2A
-
 Homo sapiens