Activating Compound | Comment | Organism | Structure |
---|---|---|---|
spermidine | activation | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression of PTP2C and DELTASH2-PTP2C in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
H3VO4 | slight effect | Homo sapiens | |
heparin | - |
Homo sapiens | |
Zn2+ | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | 4-6fold increase of activity | Homo sapiens | |
Mg2+ | 4-6fold increase of activity | Homo sapiens | |
Mn2+ | 4-6fold increase of activity | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
68000 | - |
PTP2C, gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl phosphate + H2O | - |
Homo sapiens | 4-nitrophenol + phosphate | - |
? | |
ENDpYINASL + H2O | - |
Homo sapiens | ENDYINASL + phosphate | - |
? | |
lysozyme + H2O | reduced, carboxymethylated and maleylated | Homo sapiens | ? + phosphate | - |
? | |
myelin basic protein + H2O | - |
Homo sapiens | ? + phosphate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | 5.6 | substrates 4-nitrophenyl phosphate and ENDpYINASL, enzymes PTP2C and DELTASH2-PTP2C | Homo sapiens |
6.5 | 7.5 | substrates lysozyme and myelin basic protein, enzymes PTP2C and DELTASH2-PTP2C | Homo sapiens |