Activating Compound | Comment | Organism | Structure |
---|---|---|---|
PgammaPDE6 | regulatory subunit of PDE6, activation of cGMP binding to GAF domains of PDE6alpha or beta subunit | Lithobates pipiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
PgammaPDE6 | regulatory subunit of PDE6, inhibition of catalytic activity | Lithobates pipiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
photoreceptor outer segment membrane | peripherally attached under dark conditions | Lithobates pipiens | 42622 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
guanosine 3',5'-cyclic phosphate + H2O | Lithobates pipiens | - |
guanosine 5'-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lithobates pipiens | Q8UUY2 | - |
- |
Lithobates pipiens | Q8UUY6 | - |
- |
Lithobates pipiens | Q8UUY7 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
photoreceptor | rod outer segment | Lithobates pipiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
guanosine 3',5'-cyclic phosphate + H2O | - |
Lithobates pipiens | guanosine 5'-phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | alpha,beta,gamma2, PDE6 consists of two homologous catalytic subunits and two identical regulatory subunits | Lithobates pipiens |
tetramer | alpha,beta,gamma2, PDE6 consits of two homologous catalytic subunits and two identical regulatory subunits | Lithobates pipiens |
Synonyms | Comment | Organism |
---|---|---|
cGMP phosphodiesterase | - |
Lithobates pipiens |
PDE6alpha | catalytic alpha subunit | Lithobates pipiens |
PDE6beta | catalytic beta subunit | Lithobates pipiens |
PDE6gamma | inhibitory gamma subunit | Lithobates pipiens |