Inhibitors | Comment | Organism | Structure |
---|---|---|---|
SO42- | product inhibition | Gallus gallus | |
SO42- | product inhibition | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Gallus gallus | 5764 | - |
lysosome | - |
Homo sapiens | 5764 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
19500 | - |
x * 47000 + x * 19500, enzyme from liver, SDS-PAGE | Homo sapiens |
47000 | - |
x * 47000 + x * 19500, enzyme from liver, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skin fibroblast | cell culture | Homo sapiens | - |
skin fibroblast | cell-lines from normal and Hunter's disease, i.e. idurono 2-sulfatase deficient individuals | Homo sapiens | - |
tibial chondrocyte | - |
Gallus gallus | - |
tibial chondrocyte | embryonal, cell culture | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucuronic acid 2-sulfate-2,5-anhydro-D-mannitol 6-sulfate + H2O | i.e. GSMS | Gallus gallus | D-glucuronic acid 2,5-anhydro-D-mannitol 6-sulfate + SO42- | - |
? | |
D-glucuronic acid 2-sulfate-2,5-anhydro-D-mannitol 6-sulfate + H2O | i.e. GSMS | Homo sapiens | D-glucuronic acid 2,5-anhydro-D-mannitol 6-sulfate + SO42- | - |
? | |
D-glucuronic acid 2-sulfate-2,5-anhydro-D-mannitol 6-sulfate + H2O | enzyme removes ester sulfate from 2-position | Gallus gallus | D-glucuronic acid 2,5-anhydro-D-mannitol 6-sulfate + SO42- | - |
? | |
D-glucuronic acid 2-sulfate-2,5-anhydro-D-mannitol 6-sulfate + H2O | enzyme removes ester sulfate from 2-position | Homo sapiens | D-glucuronic acid 2,5-anhydro-D-mannitol 6-sulfate + SO42- | - |
? | |
D-glucuronic acid 2-sulfate-2,5-anhydro-D-talitol 6-sulfate + H2O | i.e. GSTS | Gallus gallus | D-glucuronic acid 2,5-anhydro-D-talitol 6-sulfate + SO42- | - |
? | |
D-glucuronic acid 2-sulfate-2,5-anhydro-D-talitol 6-sulfate + H2O | i.e. GSTS | Homo sapiens | D-glucuronic acid 2,5-anhydro-D-talitol 6-sulfate + SO42- | - |
? | |
additional information | no hydrolysis of iduronate 2-sulfate residues | Gallus gallus | ? | - |
? | |
additional information | no hydrolysis of iduronate 2-sulfate residues | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 47000 + x * 19500, enzyme from liver, SDS-PAGE | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4 | - |
- |
Gallus gallus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
3 | 4.9 | about 90% of maximal activity at pH 3 and about half-maximal activity at pH 4.9 | Gallus gallus |