Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | - |
Saccharomyces cerevisiae | |
5,7-dihydroxy-2-phenyl-4H-chromen-4-one | from hexane extracts of the Indian herb Oroxylum indicum | Saccharomyces cerevisiae | |
5,7-dihydroxy-6-methoxy-2-phenyl-8-(piperidin-1-ylmethyl)-4H-chromen-4-one | - |
Rattus norvegicus | |
5,7-dihydroxy-6-methoxy-2-phenyl-8-(piperidin-1-ylmethyl)-4H-chromen-4-one | - |
Saccharomyces cerevisiae | |
5,7-dihydroxy-6-methoxy-8-(morpholin-4-ylmethyl)-2-phenyl-4H-chromen-4-one | - |
Rattus norvegicus | |
5,7-dihydroxy-6-methoxy-8-(morpholin-4-ylmethyl)-2-phenyl-4H-chromen-4-one | - |
Saccharomyces cerevisiae | |
5,7-dihydroxy-6-methoxy-8-[(4-methylpiperazin-1-yl)methyl]-2-phenyl-4H-chromen-4-one | - |
Rattus norvegicus | |
5,7-dihydroxy-6-methoxy-8-[(4-methylpiperazin-1-yl)methyl]-2-phenyl-4H-chromen-4-one | - |
Saccharomyces cerevisiae | |
acarbose | - |
Rattus norvegicus | |
baicalein | i.e. 5,6,7-trihydroxy flavone, from hexane extracts of the Indian herb Oroxylum indicum | Rattus norvegicus | |
baicalein | i.e. 5,6,7-trihydroxy flavone, from hexane extracts of the Indian herb Oroxylum indicum | Saccharomyces cerevisiae | |
chrysin | from hexane extracts of the Indian herb Oroxylum indicum | Rattus norvegicus | |
additional information | no inhibition by acarbose | Saccharomyces cerevisiae | |
oroxylin A | from hexane extracts of the Indian herb Oroxylum indicum | Rattus norvegicus | |
oroxylin A | from hexane extracts of the Indian herb Oroxylum indicum | Saccharomyces cerevisiae | |
tert-butyl 4-[(5,7-dihydroxy-6-methoxy-4-oxo-2-phenyl-4H-chromen-8-yl)methyl]piperazine-1-carboxylate | - |
Rattus norvegicus | |
tert-butyl 4-[(5,7-dihydroxy-6-methoxy-4-oxo-2-phenyl-4H-chromen-8-yl)methyl]piperazine-1-carboxylate | - |
Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
maltose + H2O | Rattus norvegicus | - |
alpha-D-glucose + D-glucose | - |
? | |
maltose + H2O | Saccharomyces cerevisiae | - |
alpha-D-glucose + D-glucose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl alpha-D-glucopyranoside + H2O | - |
Rattus norvegicus | 4-nitrophenol + alpha-D-glucose | - |
? | |
4-nitrophenyl alpha-D-glucopyranoside + H2O | - |
Saccharomyces cerevisiae | 4-nitrophenol + alpha-D-glucose | - |
? | |
maltose + H2O | - |
Rattus norvegicus | alpha-D-glucose + D-glucose | - |
? | |
maltose + H2O | - |
Saccharomyces cerevisiae | alpha-D-glucose + D-glucose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
maltase | - |
Rattus norvegicus |
maltase | - |
Saccharomyces cerevisiae |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.5 | - |
baicalein | - |
Rattus norvegicus | |
0.5 | - |
baicalein | - |
Saccharomyces cerevisiae |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0064 | - |
- |
Rattus norvegicus | acarbose | |
0.0354 | - |
- |
Rattus norvegicus | 5,7-dihydroxy-6-methoxy-8-[(4-methylpiperazin-1-yl)methyl]-2-phenyl-4H-chromen-4-one | |
0.0493 | - |
- |
Saccharomyces cerevisiae | (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | |
0.0507 | - |
- |
Rattus norvegicus | 5,7-dihydroxy-6-methoxy-2-phenyl-8-(piperidin-1-ylmethyl)-4H-chromen-4-one | |
0.075 | - |
- |
Rattus norvegicus | tert-butyl 4-[(5,7-dihydroxy-6-methoxy-4-oxo-2-phenyl-4H-chromen-8-yl)methyl]piperazine-1-carboxylate | |
0.076 | - |
- |
Rattus norvegicus | 5,7-dihydroxy-6-methoxy-8-(morpholin-4-ylmethyl)-2-phenyl-4H-chromen-4-one | |
0.08 | 4 | - |
Saccharomyces cerevisiae | tert-butyl 4-[(5,7-dihydroxy-6-methoxy-4-oxo-2-phenyl-4H-chromen-8-yl)methyl]piperazine-1-carboxylate | |
0.099 | - |
- |
Saccharomyces cerevisiae | 5,7-dihydroxy-6-methoxy-8-[(4-methylpiperazin-1-yl)methyl]-2-phenyl-4H-chromen-4-one | |
0.124 | - |
- |
Saccharomyces cerevisiae | oroxylin A | |
0.135 | - |
- |
Rattus norvegicus | oroxylin A | |
0.15 | - |
- |
Saccharomyces cerevisiae | 5,7-dihydroxy-6-methoxy-8-(morpholin-4-ylmethyl)-2-phenyl-4H-chromen-4-one | |
0.167 | - |
- |
Saccharomyces cerevisiae | 5,7-dihydroxy-6-methoxy-2-phenyl-8-(piperidin-1-ylmethyl)-4H-chromen-4-one | |
0.203 | - |
- |
Saccharomyces cerevisiae | baicalein | |
0.214 | - |
- |
Rattus norvegicus | baicalein | |
0.371 | - |
- |
Saccharomyces cerevisiae | 5,7-dihydroxy-2-phenyl-4H-chromen-4-one | |
0.375 | - |
- |
Rattus norvegicus | chrysin |