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Literature summary for 3.2.1.20 extracted from
- Neutral alpha-glucosidase activity in mouse: a marker of epididymal function? (2007), Reprod. Fertil. Dev., 19, 563-568.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| testosterone | activates the neutral alpha-glucosidase in epididymal corpus | Mus musculus |  |
Application
| Application | Comment | Organism |
|---|---|---|
| diagnostics | the neutral alpha-glucosidase might be a good epididymal marker | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| testosterone | inhibits the neutral alpha-glucosidase in epididymal cauda and caput | Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | neutral alpha-glucosidase secreted from the epididymis | Mus musculus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mus musculus | the neutral alpha-glucosidase is involved in epididymal maturation, which is different in well-fed and undernourished mice, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
adult male Albino Swiss mice | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epididymis | from well-fed and undernourished mice, cauda, caput, and corpus | Mus musculus | - |
| kidney | - |
Mus musculus | - |
| spermatozoon | epididymal | Mus musculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0106 | - |
neutral alpha-glucosidase in epididymal cauda | Mus musculus |
| 0.0117 | - |
neutral alpha-glucosidase in epididymal corpus | Mus musculus |
| 0.0154 | - |
neutral alpha-glucosidase in kidney | Mus musculus |
| 0.0226 | - |
neutral alpha-glucosidase in complete epididymis | Mus musculus |
| 0.0307 | - |
neutral alpha-glucosidase in epididymal caput | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl alpha-D-glucopyranoside + H2O | - |
Mus musculus | 4-nitrophenol + alpha-D-glucose | - |
? | |
| additional information | the neutral alpha-glucosidase is involved in epididymal maturation, which is different in well-fed and undernourished mice, overview | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NAG | - |
Mus musculus |
| neutral alpha-glucosidase | - |
Mus musculus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.3 | 7.5 | assay at, neutral alpha-glucosidase | Mus musculus |
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