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Literature summary for 3.2.1.31 extracted from
- Isolation and characterization of the major form of beta-glucuronidase from human seminal plasma (1983), Biochim. Biophys. Acta, 748, 398-404.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ag+ | - |
Homo sapiens |  |
| ascorbic acid | - |
Homo sapiens | |
| Cu2+ | - |
Homo sapiens | |
| D-saccharic acid 1,4-lactone | - |
Homo sapiens | |
| Hg2+ | reversed by EDTA | Homo sapiens | |
| Ni2+ | - |
Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.018 | 3.08 | phenolphthalein beta-D-glucuronide | dependency on pH | Homo sapiens | |
| 0.13 | 2.9 | p-nitrophenyl-beta-D-glucuronide | - |
Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 250000 | 310000 | gel filtration | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl beta-D-glucuronide + H2O | - |
Homo sapiens | 4-nitrophenol + D-glucuronic acid | - |
? | |
| phenolphthalein beta-D-glucuronide + H2O | - |
Homo sapiens | phenolphthalein + D-glucuronic acid | - |
? | |
| phenolphthalein-beta-D-glucuronide + H2O | - |
Homo sapiens | phenolphthalein + D-glucuronic acid | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | SDS-PAGE | Homo sapiens |
| tetramer | 4 * 70000-80000, man, 2 identical 2 non-identical chains | Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 70 | - |
- |
Homo sapiens |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 55 | - |
depending on pH, substrate protects against inactivation | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.3 | - |
- |
Homo sapiens |
| 4.7 | - |
- |
Homo sapiens |
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