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Literature summary for 3.2.1.58 extracted from
- The effect of pentacyclic guanidine alkaloids from the marine sponge Monanchora pulchra Lambe, 1894 on the activity of natural beta-1,3-D-glucanase from the marine fungus Chaetomium indicum Corda, 1840 and the marine bivalve mollusk Spisula sachalinensis, S (2018), Russ. J. Mar. Biol., 44, 127-134 .
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| monanchocidin A | inhibits 98.6% at 0.257 mM, irreversible slow inhibition | Dichotomopilus indicus |  |
| monanchomycalin B | inhibits 98.5% at 0.278 mM, irreversible slow inhibition | Dichotomopilus indicus | |
| additional information | inhibitory effects of pentacyclic guanidine alkaloids (monanchomycalin B, monanchocidin A, and normonanchocidin A) from the marine sponge Monanchora pulchra on exo-beta-1,3-D-glucanase ChinLam enzyme activity, compound identification by mass spectrosmetry | Dichotomopilus indicus | |
| normonanchocidin A | inhibits 99.3% at 0.287 mM, irreversible slow inhibition | Dichotomopilus indicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | Michaelis-Menten kinetics | Dichotomopilus indicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| laminarin + H2O | Dichotomopilus indicus | - |
? | - |
? | |
| additional information | Dichotomopilus indicus | exo-1,3-beta-D-glucanases remove the glucose residues or gentiobiose (Glc-beta-1,6-Glc) from the non-reducing ends of beta-1,3-D-glucans, beta-1,3-1,6-D-glucans and laminarioligosaccharides | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Dichotomopilus indicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| laminarin + H2O | - |
Dichotomopilus indicus | ? | - |
? | |
| additional information | exo-1,3-beta-D-glucanases remove the glucose residues or gentiobiose (Glc-beta-1,6-Glc) from the non-reducing ends of beta-1,3-D-glucans, beta-1,3-1,6-D-glucans and laminarioligosaccharides | Dichotomopilus indicus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| beta-1,3-glucanase | - |
Dichotomopilus indicus |
| ChinLam | - |
Dichotomopilus indicus |
| exo-beta-1,3-D-glucanase | - |
Dichotomopilus indicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Dichotomopilus indicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.2 | - |
assay at | Dichotomopilus indicus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | inhibition kinetics, upon inhibition by monanchomycalin A and monanchocidin A, a positive cooperability is observed | Dichotomopilus indicus | |
| 0.0135 | - |
normonanchocidin A | pH 5.2, 37°C | Dichotomopilus indicus | |
| 0.0894 | - |
monanchocidin A | pH 5.2, 37°C | Dichotomopilus indicus | |
| 0.2164 | - |
monanchomycalin B | pH 5.2, 37°C | Dichotomopilus indicus | |
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