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Literature summary for 3.2.1.76 extracted from

  • Clements, P.R.; Muller, V.; Hopwood, J.J.
    Human alpha-L-iduronidase. 2. catalytic properties (1985), Eur. J. Biochem., 152, 29-34.
    View publication on PubMed
Search for more literature for 3.2.1.76

Inhibitors

Inhibitors Comment Organism Structure
2,5-anhydro-D-mannitol
-
 Homo sapiens
2,5-anhydro-D-mannitol 6-sulfate
-
 Homo sapiens
CuCl2
-
 Homo sapiens
Na2SO4
-
 Homo sapiens
NaCl
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.08
-
 alpha-L-iduronosyl-(1->3)-2,5-anhydro-D-talitol 4-sulfate
-
 Homo sapiens
0.12
-
 2,5-anhydro-4-O-alpha-L-idopyranuronosyl-D-mannitol 6-sulfate
-
 Homo sapiens
0.14
-
 2,5-anhydro-3-O-alpha-L-idopyranuronosyl-D-mannitol
-
 Homo sapiens
0.82
-
 4-methylumbelliferyl-alpha-L-iduronide
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,5-anhydro-3-O-alpha-L-idopyranuronosyl-D-mannitol + H2O Homo sapiens
-
 ?
-
 ?
2,5-anhydro-4-O-alpha-L-idopyranuronosyl-D-mannitol 6-sulfate + H2O Homo sapiens
-
 ?
-
 ?
alpha-L-iduronosyl-(1->3)-2,5-anhydro-D-talitol 4-sulfate + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,5-anhydro-3-O-alpha-L-idopyranuronosyl-D-mannitol + H2O
-
 Homo sapiens ?
-
 ?
2,5-anhydro-4-O-alpha-L-idopyranuronosyl-D-mannitol 6-sulfate + H2O
-
 Homo sapiens ?
-
 ?
4-methylumbelliferyl-alpha-L-iduronide + H2O
-
 Homo sapiens ?
-
 ?
alpha-L-iduronosyl-(1->3)-2,5-anhydro-D-talitol 4-sulfate + H2O
-
 Homo sapiens ?
-
 ?