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Literature summary for 3.2.2.10 extracted from
- Degradation of pyrimidine nucleotides by enzyme systems of Streptomyces. II. Pyrimidine 5'-nucleotide phophoribo (deoxyribo) hydrolase of Streptomyces virginiae (1967), J. Gen. Appl. Microbiol., 13, 267-278.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ag+ | - |
Streptomyces virginiae |  |
| Cd2+ | - |
Streptomyces virginiae | |
| Cr3+ | - |
Streptomyces virginiae | |
| Cu2+ | - |
Streptomyces virginiae | |
| EDTA | - |
Streptomyces virginiae | |
| Hg2+ | - |
Streptomyces virginiae | |
| KCN | - |
Streptomyces virginiae | |
| p-chloromercuribenzoate | - |
Streptomyces virginiae | |
| Zn2+ | - |
Streptomyces virginiae | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 6.95 | - |
5'-UMP | - |
Streptomyces virginiae | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Streptomyces virginiae | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyrimidine 5'-nucleotides + H2O | Streptomyces virginiae | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces virginiae | - |
- |
- |
| Streptomyces virginiae IFO 3729 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Streptomyces virginiae |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 2.5 | - |
- |
Streptomyces virginiae |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -4°C, 2 months | Streptomyces virginiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5'-CMP + H2O | - |
Streptomyces virginiae | cytosine + ribose 5-phosphate | - |
? | |
| 5'-CMP + H2O | - |
Streptomyces virginiae IFO 3729 | cytosine + ribose 5-phosphate | - |
? | |
| 5'-deoxy CMP + H2O | - |
Streptomyces virginiae | cytosine + deoxyribose 5-phosphate | - |
? | |
| 5'-deoxy CMP + H2O | - |
Streptomyces virginiae IFO 3729 | cytosine + deoxyribose 5-phosphate | - |
? | |
| 5'-deoxy TMP + H2O | - |
Streptomyces virginiae | thymine + deoxyribose 5-phosphate | - |
? | |
| 5'-deoxy TMP + H2O | - |
Streptomyces virginiae IFO 3729 | thymine + deoxyribose 5-phosphate | - |
? | |
| 5'-deoxy UMP + H2O | - |
Streptomyces virginiae | uracil + deoxyribose 5-phosphate | - |
? | |
| 5'-deoxy UMP + H2O | - |
Streptomyces virginiae IFO 3729 | uracil + deoxyribose 5-phosphate | - |
? | |
| 5'-UMP + H2O | - |
Streptomyces virginiae | uracil + ribose 5-phosphate | - |
ir | |
| 5'-UMP + H2O | - |
Streptomyces virginiae IFO 3729 | uracil + ribose 5-phosphate | - |
ir | |
| pyrimidine 5'-nucleotides + H2O | - |
Streptomyces virginiae | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
pyrimidine nucleotides | Streptomyces virginiae |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 8.8 | - |
Streptomyces virginiae |
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