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Literature summary for 3.3.2.12 extracted from

  • Ferrandez, A.; Minambres, B.; Garcia, B.; Olivera, E.; Luengo, J.; Garcia, J.; Diaz, E.
    Catabolism of phenylacetic acid in Escherichia coli: Characterization of a new aerobic hybrid pathway (1998), J. Biol. Chem., 273, 25974-25986.
    View publication on PubMed
Search for more literature for 3.3.2.12

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
73045
-
 x * 73045, calculated from amino acid sequence Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli P77455 bifunctional protein, catalyzing the reactions of 2-oxepin-2(3H)-ylideneacetyl-CoA hydrolase, EC 3.3.2.12, and 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase, EC 1.17.1.7
-
Escherichia coli W14
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxepin-2(3H)-ylideneacetyl-CoA + H2O
-
 Escherichia coli 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde
-
 ?
additional information bifunctional protein, catalyzing the reactions of 2-oxepin-2(3H)-ylideneacetyl-CoA hydrolase, EC 3.3.2.12, and 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase, EC 1.17.1.7 Escherichia coli ?
-
 ?

Subunits

Subunits Comment Organism
? x * 73045, calculated from amino acid sequence Escherichia coli

Synonyms

Synonyms Comment Organism
paaZ
-
 Escherichia coli

General Information

General Information Comment Organism
malfunction disruption of the paaZ gene causes a blockade of the phenylacetate catabolic pathway Escherichia coli
metabolism the paaZ gene product is responsible of the third enzymatic step in the aerobic catabolism of phenylacetate in Escherichia coli Escherichia coli
physiological function the paaZ gene product is responsible of the third enzymatic step in the aerobic catabolism of phenylacetic acid Escherichia coli