Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Metyrapone | - |
Rattus norvegicus | |
Metyrapone | great stimulation of hydration of styrene 7,8-oxide and octene 1,2-oxide, slight stimulation of hydration of benzopyrane 4,5-oxide | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-Bromo-4'-nitroacetophenone | - |
Homo sapiens | |
2-Bromo-4'-nitroacetophenone | - |
Rattus norvegicus | |
Cyclohexene oxide | - |
Homo sapiens | |
Cyclohexene oxide | - |
Rattus norvegicus | |
Metyrapone | strong inhibition of hydration of benzopyrene 11,12-oxide and dibenzoanthracene 5,6-oxide | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
49000 | - |
x * 49000, SDS-PAGE | Homo sapiens |
49000 | - |
x * 49000, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.618 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzoanthracene 5,6-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
benzoanthracene 5,6-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
benzopyrene 11,12-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
benzopyrene 4,5-oxide + H2O | - |
Homo sapiens | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
benzopyrene 4,5-oxide + H2O | - |
Rattus norvegicus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
benzopyrene 7,8-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
benzopyrene 7,8-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
dibenzanthracene 5,6-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
dibenzanthracene 5,6-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
octene 1,2-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
octene 1,2-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
phenanthrene-9,10-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
phenanthrene-9,10-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
styrene 7,8-oxide + H2O | - |
Homo sapiens | styrene glycol | - |
? | |
styrene 7,8-oxide + H2O | - |
Rattus norvegicus | styrene glycol | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 49000, SDS-PAGE | Homo sapiens |
? | x * 49000, SDS-PAGE | Rattus norvegicus |