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Literature summary for 3.3.2.9 extracted from

  • Bornstein, W.A.; Levin, W.; Thomas, P.E.; Ryan, D.E.; Bresnick, E.
    Comparison of nuclear and microsomal epoxide hydrase from rat liver (1979), Arch. Biochem. Biophys., 197, 436-446.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
3-methylcholanthrene enhances nuclear hydration of phenanthrene-9,10-oxide, benzopyrene-11,12-oxide and octene-1,2-oxide, no significant effect on microsomal hydration Rattus norvegicus
Metyrapone stimulates Rattus norvegicus
Phenobarbital enhances nuclear and microsomal hydration of phenanthrene-9,10-oxide, benzopyrene-11,12-oxide and octene-1,2-oxide Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Rattus norvegicus
-
-
nucleus
-
Rattus norvegicus 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
49000
-
x * 49000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzoanthracene-9,10-oxide + H2O
-
Rattus norvegicus ?
-
?
benzopyrene 11,12-oxide + H2O
-
Rattus norvegicus ?
-
?
benzopyrene 4,5-oxide + H2O
-
Rattus norvegicus (-)benzopyrene 4,5-dihydrodiol
-
?
benzopyrene 7,8-oxide + H2O
-
Rattus norvegicus ?
-
?
benzopyrene 9,10-oxide + H2O
-
Rattus norvegicus ?
-
?
octene 1,2-oxide + H2O
-
Rattus norvegicus ?
-
?
phenanthrene-9,10-oxide + H2O
-
Rattus norvegicus ?
-
?
styrene 7,8-oxide + H2O
-
Rattus norvegicus styrene glycol
-
?

Subunits

Subunits Comment Organism
? x * 49000, SDS-PAGE Rattus norvegicus