Cloned (Comment) | Organism |
---|---|
expressed as a His-tagged fusion protein in 293F cells | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
MLN-4760 | conversion of Ang II to Ang(1-7) is blocked by MLN-4760 but not by DX600 | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
species differences regarding rodent and human ACE2 in terms of substrate specificity and inhibitors | - |
Purification (Comment) | Organism |
---|---|
using affinity chromatography and gel filtration | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin II + H2O | converts Ang II to Ang(1-7) | Mus musculus | ? | - |
? | |
Mca-APK-Dnp + H2O | - |
Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACE2 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | mouse ACE2 (1 mg/kg) obliterates hypertension induced by Ang II infusion by rapidly decreasing plasma Ang II | Mus musculus |