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Literature summary for 3.4.15.1 extracted from
- Some characteristics of a peptidyl dipeptidase (kininase II) from rat CSF: differential effects of NaCl on the sequential degradation steps of bradykinin (1990), J. Neurochem., 55, 1861-1869.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Rattus norvegicus |  |
| bradykinin potentiator B | - |
Rattus norvegicus | |
| captopril | - |
Rattus norvegicus | |
| EDTA | - |
Rattus norvegicus | |
| NaCl | concentration dependent inhibition of hippuryl-His-Leu between 0 and 100 mM | Rattus norvegicus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| NaCl | stimulates hydrolysis of hippuryl-His-Leu in concentration-dependent manner between 0 and 300 mM | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 230000 | - |
gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cerebrospinal fluid | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| bradykinin + H2O | - |
Rattus norvegicus | Phe-Arg + Ser-Pro + Arg-Pro-Pro-Gly-Phe | - |
? | |
| hippuryl-His-Leu + H2O | - |
Rattus norvegicus | hippuric acid + His-Leu | - |
? | |
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Release 2023.1 (January 2023)
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