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Literature summary for 3.4.17.1 extracted from
- Partial characterization of the proteolytic enzymes in the gut of the banana weevil, Cosmopolites sordidus, and effects of soybean Kunitz trypsin inhibitor on larval performance (2005), Entomol. Exp. Appl., 116, 227-236.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | complete inhibition at 1 mM | Cosmopolites sordidus |  |
| CdCl2 | 55% inhibition at 1 mM | Cosmopolites sordidus | |
| CuCl2 | complete inhibition at 1 mM | Cosmopolites sordidus | |
| DTT | 52% inhibition at 1 mM | Cosmopolites sordidus | |
| EDTA | 86% inhibition at 1 mM | Cosmopolites sordidus | |
| additional information | no or poor inhibition by soybean Kunitz trypsin inhibitor, E64, leupeptin, chymostatin, pepstatin A, N-tosyl-L-lysine chloromethyl ketone, N-tosyl-L-phenylalanine chloromethyl ketone, iodoacetic acid | Cosmopolites sordidus | |
| potato tuber carboxypeptidase inhibitor | 95% inhibition at 0.001 mM | Cosmopolites sordidus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cosmopolites sordidus | - |
banana weevil | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| gut | evenly distributed activity in the anterior and middle sections, but almost no activity in the posterior section | Cosmopolites sordidus | - |
| larva | - |
Cosmopolites sordidus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
activity in gut sections | Cosmopolites sordidus |
| 0.0064 | - |
gut extract | Cosmopolites sordidus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hippuryl-DL-phenylalanine + H2O | - |
Cosmopolites sordidus | hippuric acid + DL-phenylalanine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| carboxypeptidase A-like activity | - |
Cosmopolites sordidus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Cosmopolites sordidus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
- |
Cosmopolites sordidus |
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Release 2023.1 (January 2023)
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