ACE2 of the heart: From angiotensin I to angiotensin (1-7)
Keidar, S.; Kaplan, M.; Gamliel-Lazarovich, A.; Cardiovasc. Res. 73, 463-469 (2007) 
Data extracted from this reference:
Inhibitors
Inhibitors
Commentary
Organism
Structure
DX600
-
Rattus norvegicus
DX600
-
Mus musculus
Organism
Organism
UniProt
Commentary
Textmining
Mus musculus
-
-
-
Rattus norvegicus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
heart
-
Mus musculus
-
kidney
-
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
angiotensin I + H2O
-
679072
Mus musculus
angiotensin-(1-9) + Leu
-
-
-
?
angiotensin I + H2O
-
679072
Rattus norvegicus
angiotensin-(1-9) + Leu
-
-
-
?
angiotensin II + H2O
-
679072
Mus musculus
angiotensin-(1-7) + Phe
-
-
-
?
angiotensin II + H2O
-
679072
Rattus norvegicus
angiotensin-(1-7) + Phe
-
-
-
?
apelin-13 + H2O
high catalytic efficiency
679072
Mus musculus
?
-
-
-
?
apelin-13 + H2O
high catalytic efficiency
679072
Rattus norvegicus
?
-
-
-
?
apelin-36 + H2O
high catalytic efficiency
679072
Mus musculus
?
-
-
-
?
apelin-36 + H2O
high catalytic efficiency
679072
Rattus norvegicus
?
-
-
-
?
beta-casomorphin + H2O
-
679072
Mus musculus
?
-
-
-
?
beta-casomorphin + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
des-Arg9-bradykinin + H2O
-
679072
Mus musculus
?
-
-
-
?
des-Arg9-bradykinin + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
dynorphin A + H2O
-
679072
Mus musculus
?
-
-
-
?
dynorphin A + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
Lys-des-Arg9-bradykinin + H2O
-
679072
Mus musculus
?
-
-
-
?
Lys-des-Arg9-bradykinin + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
additional information
ACE2 functions as a carboxymonopeptidase with a preference for C-terminal Leu or Phe, ACE2 counterbalances the enzymatic actions of ACE, ACE2 does not metabolize bradykinin
679072
Mus musculus
?
-
-
-
-
additional information
ACE2 functions as a carboxymonopeptidase with a preference for C-terminal Leu or Phe, ACE2 counterbalances the enzymatic actions of ACE, ACE2 does not metabolize bradykinin
679072
Rattus norvegicus
?
-
-
-
-
neurotensin + H2O
-
679072
Mus musculus
?
-
-
-
?
neurotensin + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
ACE2
-
Mus musculus
ACE2
-
Rattus norvegicus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
DX600
-
Rattus norvegicus
DX600
-
Mus musculus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
heart
-
Mus musculus
-
kidney
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
angiotensin I + H2O
-
679072
Mus musculus
angiotensin-(1-9) + Leu
-
-
-
?
angiotensin I + H2O
-
679072
Rattus norvegicus
angiotensin-(1-9) + Leu
-
-
-
?
angiotensin II + H2O
-
679072
Mus musculus
angiotensin-(1-7) + Phe
-
-
-
?
angiotensin II + H2O
-
679072
Rattus norvegicus
angiotensin-(1-7) + Phe
-
-
-
?
apelin-13 + H2O
high catalytic efficiency
679072
Mus musculus
?
-
-
-
?
apelin-13 + H2O
high catalytic efficiency
679072
Rattus norvegicus
?
-
-
-
?
apelin-36 + H2O
high catalytic efficiency
679072
Mus musculus
?
-
-
-
?
apelin-36 + H2O
high catalytic efficiency
679072
Rattus norvegicus
?
-
-
-
?
beta-casomorphin + H2O
-
679072
Mus musculus
?
-
-
-
?
beta-casomorphin + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
des-Arg9-bradykinin + H2O
-
679072
Mus musculus
?
-
-
-
?
des-Arg9-bradykinin + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
dynorphin A + H2O
-
679072
Mus musculus
?
-
-
-
?
dynorphin A + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
Lys-des-Arg9-bradykinin + H2O
-
679072
Mus musculus
?
-
-
-
?
Lys-des-Arg9-bradykinin + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
additional information
ACE2 functions as a carboxymonopeptidase with a preference for C-terminal Leu or Phe, ACE2 counterbalances the enzymatic actions of ACE, ACE2 does not metabolize bradykinin
679072
Mus musculus
?
-
-
-
-
additional information
ACE2 functions as a carboxymonopeptidase with a preference for C-terminal Leu or Phe, ACE2 counterbalances the enzymatic actions of ACE, ACE2 does not metabolize bradykinin
679072
Rattus norvegicus
?
-
-
-
-
neurotensin + H2O
-
679072
Mus musculus
?
-
-
-
?
neurotensin + H2O
-
679072
Rattus norvegicus
?
-
-
-
?
Other publictions for EC 3.4.17.23
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)