Literature summary for 3.4.17.23 extracted from

Wang, L.; Wang, Y.; Yang, T.; Guo, Y.; Sun, T.
Angiotensin-converting enzyme 2 attenuates bleomycin-induced lung fibrosis in mice (2015), Cell. Physiol. Biochem., 36, 697-711 .

Search for more literature for 3.4.17.23

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q8R0I0	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

General Information

General Information	Comment	Organism
physiological function	exogenous ACE2 attenuates bleomycin-induced lung fibrosis by reversing the reduction of local ACE2 and by suppressing the elevation of angiotensinogen. ACE2 decreases the apoptosis index and leukocyte common antigen levels and ameliorates the dynamic change in surfactant-associated protein SP-A level. Reductions of TGF-beta1 and alpha-SMA are also found in ACE2-treated mice	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)