Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | 5-10 mM inhibit; activation below | Homo sapiens | |
diisopropyl fluorophosphate | - |
Homo sapiens | |
dithiothreitol | - |
Homo sapiens | |
EDTA | - |
Homo sapiens | |
Hg2+ | - |
Homo sapiens | |
iodoacetamide | - |
Homo sapiens | |
L-1-chloro-3-(4-tosylamido)-7-amino-2-heptanone | - |
Homo sapiens | |
MnCl2 | - |
Homo sapiens | |
phenylmethanesulfonyl fluoride | - |
Homo sapiens | |
Zn2+ | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi membrane | - |
Homo sapiens | 139 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | required | Homo sapiens | |
Ca2+ | 5-10 mM inhibit | Homo sapiens | |
Ca2+ | half-maximal activity at: 0.2 mM | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | no processing of: human lactase-phlorizin hydrolase | Homo sapiens | ? | - |
? | |
Protective antigen component of anthrax toxin + H2O | cleavage at the sequence Arg-Lys-Lys-Arg | Homo sapiens | ? | - |
? | |
tert-butoxycarbonyl-Arg-Val-Arg-Arg-4-methylcoumarin 7-amide + H2O | - |
Homo sapiens | tert-butoxycarbonyl-Arg-Val-Arg-Arg + 7-amino-4-methylcoumarin | - |
? |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 8.5 | more than 50% of activity maximum at pH 6.0 and 8.5 | Homo sapiens |